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Author Topic: Clinical trial of Nilotinib for tumor suppression  (Read 2077 times)

mk

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Clinical trial of Nilotinib for tumor suppression
« on: March 16, 2011, 05:26:54 pm »

I learned that the University Health Network in Toronto is conducting a clinical trial for a drug called Nilotinib. This has been used for treatment of leukemia, but apparently the researchers at UHN believe that it may be also effective for benign tumors and specifically ANs. I don't know if such studies have been conducted anywhere else. Anyway, here is the link:

http://clinicaltrialsfeeds.org/clinical-trials/show/NCT01201538

Marianna
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GK on April 23rd 2008 for 2.9 cm AN at Toronto Western Hospital. Subsequent MRIs showed darkening initially, then growth. Retrosigmoid surgery on April 26th, 2011 with Drs. Akagami and Westerberg at Vancouver General Hospital. Graduallly lost hearing after GK and now SSD but no other issues.

lori67

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Re: Clinical trial of Nilotinib for tumor suppression
« Reply #1 on: March 16, 2011, 05:43:26 pm »
Wow!  Thanks for sharing that!

Sure hope it works!  That would be amazing!

Lori
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Right 3cm AN diagnosed 1/2007.  Translab resection 2/20/07 by Dr. David Kaylie and Dr. Karl Hampf at Baptist Hospital in Nashville.  R side deafness, facial nerve paralysis.  Tarsorraphy and tear duct cauterization 5/2007.  BAHA implant 11/8/07. 7-12 nerve jump 9/26/08.

CHD63

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Re: Clinical trial of Nilotinib for tumor suppression
« Reply #2 on: March 17, 2011, 06:56:33 am »
Very interesting study.  I have bookmarked it to watch for results.

Thanks for sharing this information.

Clarice
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Right MVD for trigeminal neuralgia, 1994, Pittsburgh, PA
Left retrosigmoid 2.6 cm AN removal, February, 2008, Duke U
Tumor regrew to 1.3 cm in February, 2011
Translab AN removal, May, 2011 at HEI, Friedman & Schwartz
Oticon Ponto Pro abutment implant at same time; processor added August, 2011

Mickey

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Re: Clinical trial of Nilotinib for tumor suppression
« Reply #3 on: March 17, 2011, 04:33:45 pm »
Very interesting! To me I believe it is very logical that someday there will be some kind of "pill" treatment other than the options we have. As a W+W patient I`ve looked for and have been taking anything associated with the chance of halting growth in my AN. So far so good goin into 4 years, knock on wood. Best wishes, Mickey
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