Author Topic: how to read this study? GK vs LINAC systems  (Read 431 times)

Berta

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how to read this study? GK vs LINAC systems
« on: May 31, 2024, 10:40:04 am »
This study (2021) is one of the few I've found that compares GK vs LINAC. I'm having trouble understanding this conclusion: GK decreased odds of trigeminal nerve (TN) impairment ….while LINAC did not impact TN function. Isn't that the same thing? Anyone out there better at understanding the difference here??

Here's the link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579095/
Diagnosed in 2019 at 3mmx4mm; last MRI in January 2024 - 7mm x 5.5 x 5 mm (TV x SI x AP). Currently investigating radiotherapy/proton beam options.

donjehle

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Re: how to read this study? GK vs LINAC systems
« Reply #1 on: June 02, 2024, 06:31:47 pm »
The way I read it is that neither GL nor LINAC has much of an impact on Trigeminal Nerve impairment (which I would guess is probably true with all radiation treatment), but GK is slightly better (OR 0.71, 95% CI 0.41-1.22) versus (OR 1.13, 95% CI 0.64-2.00) for LINAC.  And LINAC is slightly better when it comes to Tinnitus (OR 0.15, 95% CI 0.03-0.87) versus (OR 0.70, 95% CI 0.48-1.01) for GK. 

The telling statement may be the final statement: "Future studies are warranted to investigate the efficacy of GK and LINAC SRS more directly."

So, this study by itself may not be persuasive in choosing CK or LINAC over the other.  More research needs to be done.

At least that's how I understand it.

Burning Tongue, Loss of Hearing & Balance, and Tinnitus led to MRI. Very small AN found on 11/23/2021
While watching and waiting, lost significant hearing. WRS now at 12% (down from 100%). Was fitted with CROS system on 3/7/22.  Stable MRI on 7/29/22
No treatment yet.

mwatto

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Re: how to read this study? GK vs LINAC systems
« Reply #2 on: June 04, 2024, 07:23:48 pm »
So I have had 5 years of atypical trigeminal type pain after Cyberknife which have mystified my specialist. My AN is ipsilateral to the trigeminal nerve so I thought it was that however even with a focus of the MRI on that nerve all seemed normal. Yest stabbbing eye and ear and throat and deep in head that side (could never sleep on that side either) would wake me up almost every night. I saw a neurosurgeon this year for his opinion  as he also a TN specialist. He said in his opinion nothing to do with AN (and he operates on that quite a bit) he thought I might have had Herpes simplex viral reactivation especially since I had the vaccine and Covid and RSV post my treatment. My dentist and my doctor said TMJ so I got a dental mouth guard which helped a little. Then about three months ago I saw my naturopath a biochemist and he said lets try high dose PEA and a few other things. This stopped the pain and it has not returned. Full spectrum CBD, CBG and CBN have also helped I think. Anyway am completely pain free for a few months now. Sleeping well also (a few things am taking such as Ecklonia Cava).
Michele
20 x19x14mm Cystic AN diagnosed Feb 2019. CK.
Mri 2019 shrinking: 18x17x13 mm.
Mri 2020 - no cysts visible stable.
MRI 2021 stable no change
MRI 2022 stable no change.
MRI 2023 Further reduction 12x12x10mm!! Hearing 85%
MRI 2024: No change AN or hearing